Handbook of Pharmaceutical Granulation Technology

Handbook of Pharmaceutical Granulation Technology Free Download

DESCRIPTION

Integrating the basic principles and industrial practices of pharmaceutical granulation production, this book discusses technologies and demonstrates cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements. Specialists from pharmaceutical companies, academia, and the U.S. Drug Regulatory Affairs agency address current and changing practices in industrial drug granulation production. Text, charts, figures, and photographs illustrate the pros and cons of diverse methods and technologies for accurately achieving strong bonding of particles in tablets and capsules

Introduction, D. M. Parikh 
Theory of Granulation, L.L. Augsburger and M.K. Vuppala 
Drug Substance and Excipient Characterization, P.W.S. Heng and L.W.Chan 
Binders and Solvents, R.K. Khankari and J. Hontz 
Spray Drying as an Alternative Granulation Technique, F.V. Shaw 
Roller Compaction Technology, R.W. Miller 
High Shear Mixer Granulators, P. Holm 
Low Shear Granulators, T. Chirkot and C. W. Propst 
Batch Fluid Bed Granulation, D.M. Parikh, J.A. Bonck, and M. Mogavero 
Single-Pot Processing, T.P. Garcia and L.J. Lucisano 
Extrusion-Spheronization as a Granulation Technique, D.F. Erkoboni 
Continuous Granulation, M. Bonde 
Sizing of Granulation, G. S. Rekhi and M.K. Vuppala 
Granulation Characterization: Methods and Significance, C.M. Sinko 
Bioavailability and Granule Properties, S.S. Jambhekar 
Regulatory Issues in Granulation Processes, G.A. Hileman 


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